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Grahame Hardie

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Grahame Hardie
Born5 April 1950
Known forDiscovery of AMP-activated protein kinase
Scientific career
FieldsBiochemistry
InstitutionsUniversity of Dundee
ThesisCereal Carbohydrases (1974)
Websitewww.lifesci.dundee.ac.uk/people/grahame-hardie

David Grahame Hardie (born 1950) is a Scottish biochemist, and Professor of Cellular Signalling, at the School of Life Sciences, University of Dundee.[1]

Career and research

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He was a member of the Faculty of 1000.[2] He is known for the discovery of AMP-activated protein kinase (AMPK).[3]

Publications

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  • "Regulation of AMP-activated protein kinase by natural and synthetic activators", Acta Pharmaceutica Sinica B (2016) 6, (1–19)
  • "AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer", Biochemical Society Transactions (2011) 39, (1–13)
  • D. Grahame Hardie, ed. (1999). "Analysis of signal transduction pathways using protein serine - threonine phosphate inhibitors". Protein phosphorylation: a practical approach. Oxford University Press. ISBN 978-0-19-963729-4.
  • Biochemical messengers: hormones, neurotransmitters, and growth factors. Springer. 1991. ISBN 978-0-412-30350-0.

References

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  1. ^ "Professor Grahame Hardie FRS, FRSE, FMedSci". 30 August 2013.
  2. ^ "David Grahame Hardie - F1000Prime".
  3. ^ Winder WW, Hardie DG (July 1999). "AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes". The American Journal of Physiology. 277 (1): E1-10. doi:10.1152/ajpendo.1999.277.1.E1. PMID 10409121.
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